How bad is acinic cell carcinoma?

Acinic cell carcinoma (AciCC) of salivary gland is a relatively infrequent tumor. Though known for its low-grade behavior, its unpredictable element of recurrence and malignancy should never be ignored.

What is acinic cell carcinoma?

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.

Is acinic cell carcinoma curable?

Prognosis is good for acinic cell carcinoma of the parotid gland, with five-year survival rates approaching 90%, and 20-year survival exceeding 50%. Patients with acinic cell carcinomas with high grade transformation (sometimes also called dedifferentiation) have significantly worse survival.

Does acinic cell carcinoma spread?

Although acinic cell carcinomas rarely metastasize, they have a high tendency to recur locally if they are incompletely excised. We describe a patient with acinic cell tumor arising in the parotid gland, with metastases to the contralateral orbit, submandibular salivary gland, and submandibular lymph node.

Is acinic cell carcinoma hereditary?

The histologic features of both neoplasms were typical of acinic cell carcinoma. While this may represent a coincidental event, the possibility that this familial occurrence is a manifestation of common genetic or environmental risk cannot be excluded.

What is warthin’s tumor?

Warthin tumor is a benign (noncancerous) tumor of the salivary glands. They most commonly arise in the parotid glands, the largest salivary glands which are located in each cheek above the jaw in front of the ears.

What causes acinic cell carcinoma?

Acinic cell carcinoma is more prevalent in women than in men. The exact cause of salivary gland cancers, including acinic cell carcinoma, is unknown; however, research suggests that possible causes of the disease may be previous exposure to radiation, wood dust inhalation, and a family history of salivary cancers.

What happens when the parotid gland is removed?

Permanent damage is possible but usually occurs in only the most difficult cases. Depending on the branch of the nerve that is damaged you may experience: • Weakness of the lower lip, leading to a slightly crooked smile. Weakness of the eyelids, making it difficult to keep the eye closed.

Do Warthins tumors come back?

The local recurrence rate is low; when recurrence does occur, it is probably due to multifocal tumors or inadequate excision. Malignant transformation in a Warthin tumor is extremely rare; however, there are a few reported examples in both the epithelial and the lymphoid component.

How bad is acinic cell carcinoma? Acinic cell carcinoma (AciCC) of salivary gland is a relatively infrequent tumor. Though known for its low-grade behavior, its unpredictable element of recurrence and malignancy should never be ignored. What is acinic cell carcinoma? Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of…