Is PVL the same as MRSA?

PVL is a toxin produced by certain types of Staphylococcus aureus. The types of Staphylococcus aureus that produce PVL can be an antibiotic sensitive Staphylococcus aureus or one that can be resistant to certain antibiotics and this is called MRSA.

Is PVL a traumatic brain injury?

PVL is a type of brain injury commonly found in babies who are very premature and have a very low birth weight. It is damage to the white matter around the fluid-filled ventricles of the brain. White matter transmits messages between different nerve cells and parts of the brain.

Can PVL resolve itself?

If cysts are detected, they may appear to resolve themselves over the course of a month or more, but the longer-term damage from PVL will likely not appear until months later. Generally speaking, damage from PVL affects motor control and may lead to a diagnosis of cerebral palsy.

Can PVL go away?

In some mild cases, the condition causes no symptoms. There is no treatment to cure PVL. Babies at risk for PVL may need special care after discharge from the hospital. Follow-up may include physical therapy, occupational therapy, and speech therapy.

How do I get rid of PVL?

If PVL is likely to be MRSA, treat empirically with two agents and then be guided by antibiotic susceptibility results, and by advice of microbiologist/hospital: rifampicin plus doxycycline (not children), sodium fusidate or trimethoprim; alternatively clindamycin alone. Third-line treatment: linezolid.

What are the symptoms of periventricular leukomalacia ( PVL )?

The prognosis for individuals with PVL depends upon the severity of the brain damage. Some children exhibit fairly mild symptoms, while others have significant deficits and disabilities. Periventricular leukomalacia (PVL) is characterized by the death of the white matter of the brain due to softening of the brain tissue.

Why are premature babies at risk for PVL?

It can affect fetuses or newborns, and premature babies are at the greatest risk of the disorder. PVL is caused by a lack of oxygen or blood flow to the area around the ventricles of the brain, which results in the death of brain tissue.

When does PVL occur in the human brain?

PVL occurs because brain tissue has been injured or has died. A lack of blood flow to the brain tissue before, during, or after birth causes PVL. It is rarely possible to tell when or why this happens. PVL is sometimes linked to bleeding inside the brain (intraventricular hemorrhage).

What is the prognosis for PVL in children?

The prognosis for individuals with PVL depends upon the severity of the brain damage. Some children exhibit fairly mild symptoms, while others have significant deficits and disabilities.

Is PVL the same as MRSA? PVL is a toxin produced by certain types of Staphylococcus aureus. The types of Staphylococcus aureus that produce PVL can be an antibiotic sensitive Staphylococcus aureus or one that can be resistant to certain antibiotics and this is called MRSA. Is PVL a traumatic brain injury? PVL is a…