What are chondrocyte cells?

Chondrocytes (/ˈkɒndrəsaɪt, -droʊ-/, from Greek χόνδρος, chondros = cartilage + κύτος, kytos = cell) are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.

What are articular chondrocytes?

The chondrocyte is the resident cell type in articular cartilage. Chondrocytes are highly specialized, metabolically active cells that play a unique role in the development, maintenance, and repair of the ECM.

What is the function of chondrocytes cells?

Chondrocytes in the AC proliferate and secrete extracellular matrix to maintain and sustain the cartilage. The cells themselves are separated from each other by cartilage matrix [2]. They respond to outside stimuli and tissue damage, and are also responsible for degenerative conditions, such as osteoarthritis (OA).

What is the function of healthy articular cartilage?

Articular cartilage is the smooth, white tissue that covers the ends of bones where they come together to form joints. Healthy cartilage in our joints makes it easier to move. It allows the bones to glide over each other with very little friction. Articular cartilage can be damaged by injury or normal wear and tear.

Are chondrocytes found in cartilage?

Cartilage cells, called chondrocytes, occur at scattered sites through the cartilage and receive nutrition by diffusion through the gel; cartilage contains no blood vessels or nerves, unlike bone.

Which have a rich supply of blood bones or cartilage?

The bones have a rich blood supply. The growth pattern of the bone is bidirectional. The growth pattern of the cartilage is unidirectional.

Are chondrocytes involved in cell division?

During this process, known as endochondral ossification, chondrocytes proliferate, produce type II collagen, and form a columnar cell layer. Subsequently they undergo cell cycle arrest, differentiation, and hypertrophy, which is followed by mineralization of the surrounding matrix.

What are chondrocyte cells? Chondrocytes (/ˈkɒndrəsaɪt, -droʊ-/, from Greek χόνδρος, chondros = cartilage + κύτος, kytos = cell) are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. What are articular chondrocytes? The chondrocyte is the resident cell type in articular cartilage. Chondrocytes…