What does cetuximab rash look like?

Patients may develop a rash. While this rash may look like acne, it is not, and should not be treated with acne medications. The rash may appear red, swollen, crusty and dry and feel sore. You may also develop very dry skin, which may crack, be itchy or become flaky or scaly.

What are the side effects of cetuximab?

The following side effects are common (occurring in greater than 30%) for patients taking cetuximab:

Skin reactions: In most people, this will present as an acne like rash and will develop within the first 2 weeks of therapy.
Generalized weakness, fatigue.
Weight loss and poor appetite.
Diarrhea.
Nausea and Vomiting.

Can cetuximab cure cancer?

Erbitux Offers ‘cure’ Potential To 3 Out Of 4 Advanced Colon Cancer Patients – But Conditions Apply. Researchers have narrowed down the conditions in metastatic colorectal cancer (mCRC) where treatment with the targeted biologic therapy Erbitux (cetuximab) is most likely to succeed.

How do you treat acneiform rash?

Treatment Recommendations Prevention of acneiform rash caused by EGFR inhibitors includes topical corticosteroids (hydrocortisone 2.5%, alclometasone) and oral antibiotics (minocycline, doxycycline, or antibiotics covering skin flora) twice daily for at least the first 6 weeks.

How do you treat cetuximab rash?

Topical antibiotic treatment with clindamycin 1% gel, erythromycin 3% gel/cream, or metronidazole 0.75%–1% cream/gel can be used 2 times per day until improvement to grade 1. Benzoyl peroxide should be avoided. For lesions of the scalp, erythromycin 2% lotion can be applied.

What does chemo rash look like?

The chemo rash typically looks like a group of small pimples and pus-filled blisters. People with this form of chemo rash may also experience pain and itchiness from the condition. Radiation dermatitis is often a side effect of receiving radiation treatment.

Does cetuximab cause hair loss?

With some of the newer types of treatments, such as erlotinib, cetuximab, panitumumab, sorafenib and vemurafenib, the hair progressively can become thin, curly and dry, but it does not completely fall out. In these cases, the thinning is usually temporary.

Is cetuximab a chemo?

Cetuximab is an IgG1 monoclonal antibody to the epidermal growth factor receptor (EGFR) and it exerts clinical activity in mCRC patients who are chemotherapy-resistant[6-8].

Is cetuximab chemo or immunotherapy?

Immunotherapy with cetuximab, may induce changes in body’s immune system and may interfere with the ability of tumor cells to grow and spread. Giving cemiplimab, platinum-doublet chemotherapy, and cetuximab may kill more tumor cells.

Is cetuximab a chemotherapy?

Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread.

Is cetuximab toxic?

The major side effect associated with cetuximab treatment is skin toxicity, including skin rash, dry skin, hair growth disorders, pruritus, and nail changes [15, 16].

Are there any side effects to taking cetuximab?

The major side effect associated with cetuximab treatment is skin toxicity, including skin rash, dry skin, hair growth disorders, pruritus, and nail changes [ 15, 16 ]. Cutaneous toxicity can severely impact patients’ physical, psychological, and social well-being and can lead to treatment discontinuation and dose reduction.

Which is the most common skin toxicity associated with cetuximab?

Skin toxicities include skin rash, skin dryness (xerosis), pruritus, paronychia, hair abnormality, mucositis, and increased growth of the eyelashes or facial hair [ 15, 44 – 47 ]. The most common toxicity is a papulo-pustular eruption, which affects 60%–80% of patients.

Where is the EGFR binding site of cetuximab?

Cetuximab (Erbitux; Merck-Serono, Darmstadt, Germany) is a human-murine chimeric monoclonal antibody directed to the epidermal growth factor receptor (EGFR) binding site [ 1 – 4 ].

What does cetuximab rash look like? Patients may develop a rash. While this rash may look like acne, it is not, and should not be treated with acne medications. The rash may appear red, swollen, crusty and dry and feel sore. You may also develop very dry skin, which may crack, be itchy or become…