What drug class is Zofran?

5-HT3 antagonist
Ondansetron/Classification

What are hydrochlorothiazide contraindications?

Who should not take HYDROCHLOROTHIAZIDE?

sympathectomy.
diabetes.
increased activity of the parathyroid gland.
high cholesterol.
a type of joint disorder due to excess uric acid in the blood called gout.
low amount of magnesium in the blood.
high amount of calcium in the blood.
low amount of sodium in the blood.

What type of injection is Zofran?

Zofran (ondansetron hydrochloridc) Injection is an antiemetic (anti nausea and vomiting) used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy)….

Adverse Reactiona,b	ZOFRAN Injection 4 mg Intravenous (n = 547)	Placebo (n = 547)
Paresthesia	9 (2%)	2 (< 1%)

Is Zofran a CYP3A4 inhibitor?

In vitro metabolism studies have shown that ondansetron is a substrate for human hepatic cytochrome P-450 enzymes, including CYP1A2, CYP2D6, and CYP3A4. In terms of overall ondansetron turnover, CYP3A4 played the predominant role.

What is the other name for hydrochlorothiazide?

Hydrochlorothiazide (HCTZ) is a thiazide diuretic (aka a “water pill”) used to treat high blood pressure or swelling (edema) by helping your body get rid of excess water and salt. It’s sold as a generic drug and under the brand names Microzide, HydroDiuril, and Oretic.

Can Zofran be given IV push?

The first dose is to be administered 30 minutes before the start of moderately to highly emetogenic chemotherapy. Subsequent doses (0.15 mg/kg up to a maximum of 16 mg per dose) are administered 4 and 8 hours after the first dose of ZOFRAN. The drug should be infused intravenously over 15 minutes.

Can Zofran be given every 4 hours?

Zofran should be administered immediately before chemotherapy as a single intravenous dose of 0.15 mg/kg. The single intravenous dose must not exceed 8 mg. Two further intravenous doses may be given in 4-hourly intervals. Oral dosing can commence 12 hours later and may be continued for up to 5 days (Table 2).

What is the pharmacology of Zofran ondansetron?

1. ONDANSETRON (ZOFRAN) GI PHARMACOLOGY Dana Luery 2. About Ondansetron ■ Generic Name – Ondansetron – Ondansetron Hydrochloride ■ Brand Name – Zofran ■ Different Formulations of Drug Available – Oral tablets – IV infusion – Rectal Suppository – Injections

What is the generic name for Zofran 5HT3 receptor antagonist?

Zofran. Generic name: ondansetron (oral) (on DAN se tron) Brand name: Zofran, Zofran ODT, Zuplenz. Drug class: 5HT3 receptor antagonists. Medically reviewed by Drugs.com. Last updated on Oct 26, 2020.

What are the side effects of hydrochlorothiazide in humans?

1 weakness; 2 feeling like you might pass out; 3 severe pain in your upper stomach spreading to your back, nausea and vomiting; 4 fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or 5 electrolyte imbalance.

Which is the correct chemical classification of hydrochlorothiazide?

The chemical classification of hydrochlorothiazide is Thiazides. Hydrochlorothiazide is a benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

What drug class is Zofran? 5-HT3 antagonist Ondansetron/Classification What are hydrochlorothiazide contraindications? Who should not take HYDROCHLOROTHIAZIDE? sympathectomy. diabetes. increased activity of the parathyroid gland. high cholesterol. a type of joint disorder due to excess uric acid in the blood called gout. low amount of magnesium in the blood. high amount of calcium in the…