What is a hemolytic agent?

Substances that are toxic to blood in general, including the clotting mechanism; hematotoxins may refer to the hematopoietic system. Descriptor ID. D053878.

Which metal can cause hemolysis?

Metals (chromium/chromates, platinum salts, nickel compounds, copper, lead, cis-platinum) Nitrites. Nitrofurantoin. Penicillin.

Is hemolytic anemia genetic?

Hemolytic anemia can be inherited or acquired: Inherited hemolytic anemia happens when parents pass the gene for the condition on to their children. Acquired hemolytic anemia is not something you are born with. You develop the condition later.

Does hemolysis affect potassium?

Of all routine blood tests plasma/serum potassium measurement is one of the most sensitive to the effect of hemolysis because red-cell potassium concentration is so much higher than that of plasma (approximately 20 times higher); hemolysis causes a spuriously high plasma potassium concentration.

Why does hemolysis affect potassium?

What does slight hemolysis on blood results mean?

A patient with mild hemolysis may have normal hemoglobin levels if increased RBC production matches the rate of RBC destruction. However, patients with mild hemolysis may develop marked anemia if their bone marrow erythrocyte production is transiently shut off by viral (parvovirus B-19) or other infections.

What does cytolysin stand for in scientific terms?

Cytolysin refers to the substance secreted by microorganisms, plants or animals that is specifically toxic to individual cells, in many cases causing their dissolution through lysis. Cytolysins that have a specific action for certain cells are named accordingly.

How are cytolysins harmful to the human body?

Cytolysins can destruct membranes without creating lysis to cells. Therefore, “membrane damaging toxins” (MDTs) describes the essential actions of cytolysins. Cytolysins comprise more than 1/3 of all bacterial protein toxins. Bacterial protein toxins can be highly poisonous to human.

What is the crystal structure of a cytolysin?

Rossjohn et al. present the crystal structure of perfringolysin O, a thiol -activated cytolysin, which creates membrane holes on eukaryotic cells. A detailed model of membrane channel formation that reveals membrane insertion mechanism is constructed.

How are cytolysins produced by a microorganism?

The cytolysins are produced by certain microorganisms at first. Sometimes the producer organism needs to create a pore at its own membrane to release such cytolysins, like the case colicins produced by Escherichia coli. Cytolysins are released as protein monomers in a water-soluble state in this step.

What is a hemolytic agent? Substances that are toxic to blood in general, including the clotting mechanism; hematotoxins may refer to the hematopoietic system. Descriptor ID. D053878. Which metal can cause hemolysis? Metals (chromium/chromates, platinum salts, nickel compounds, copper, lead, cis-platinum) Nitrites. Nitrofurantoin. Penicillin. Is hemolytic anemia genetic? Hemolytic anemia can be inherited or acquired:…