What is chalcone used for?

Currently, chalcone derivatives have been widely used for the treatment of viral disorders, cardiovascular diseases, stomach cancer, food additives, and cosmetic formulation ingredients [5]. However, much of the pharmacological potential of chalcones and their recent updates need to be understood.

What is the formula of chalcone?

C15H12O
Chalcone/Formula

What color is chalcone?

The bright yellow-colored chalcones found in many plants and in some families contribute significantly in the pigmentation of corolla. Chalcones can be synthesized in the laboratory by aldol condensation between a benzaldehyde and an acetophenone in the presence of base (Fig.

Why is chalcone yellow?

Parallel to the monooxygenase flavonoid 3′-hydroxylase, the enzyme chalcone 3-hydroxylase catalyzes the hydroxylation at the C3-position of the A-ring of chalcones. This additional hydroxyl group causes a shift of light absorption and leads to a slightly different yellow tone when the chalcone is accumulated in plants.

How do you cook chalcone?

The procedure involves grinding acetophenone with one equivalent of sodium hydroxide and benzaldehyde derivative for ten minutes using a mortar and pestle. Each chalcone is then isolated by suction filtration after washing with water.

What is chalcone derivatives?

Among these raw materials, chalcone derivatives are the precursors used for the synthesis of flavonoids, which have been applied as anti-diabetic (Zhang et al., 2015), antiplatelet, anti-inflammatory (Lin et al., 2019), anti-allergic, antimicrobial (Yibcharoenporn et al., 2019), antioxidant, and anti-cancer agents (Cai …

How do you synthesis chalcone?

Chalcone is synthesized by Claisen-Schmidt condensation, which involves the cross-aldol condensation of aldehydes and ketones with a base or acid catalyst followed by a dehydration reaction. Chalcone is a common natural pigment and one of the important intermediaries in flavonoid biosynthesis [2].

What kind of chemical compound is a chalcone?

Chalcone is an aromatic ketone and an enone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones or chalconoids.

Which is the central core of a chalcone?

Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. They show antibacterial, antifungal, antitumor and anti-inflammatory properties. They are also intermediates in the biosynthesis of flavonoids, which are substances widespread in plants…

What are the Biologi-Cal activities of chalcones?

Chalcone is an aromatic ketone that forms a central core for a variety of important biologi- cal compounds, which are collectively known as chalcones. They possess different activities like antibacterial, antifungal, anti-inflammatory and anti tumor etc depending on the sub- stitution made on them.

Why are chalcones important in the treatment of cancer?

Chalcones exhibit a broad spectrum of biological activity and thus have attracted more and more attention due to their anticancer and chemopreventive effects. Chemoprevention is one of the most promising approaches for arresting many types of cancer cells or reversing the process of carcinogenesis.

What is chalcone used for? Currently, chalcone derivatives have been widely used for the treatment of viral disorders, cardiovascular diseases, stomach cancer, food additives, and cosmetic formulation ingredients [5]. However, much of the pharmacological potential of chalcones and their recent updates need to be understood. What is the formula of chalcone? C15H12O Chalcone/Formula What color…