What is pilocarpine hcl used for?

Pilocarpine is used to treat dry mouth caused by radiotherapy in people with head and neck cancer and to treat dry mouth in people with Sjogren’s syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth).

How long does pilocarpine take to work?

You may start to feel some benefit in 1 to 2 weeks. However, it may take up to 3 months to feel the full benefit. Tell your doctor if your condition persists or worsens.

When is the best time to take pilocarpine?

Take your doses during (or straight after) a meal, and make sure you take your last dose of the day with your evening meal. If you are taking pilocarpine because you have Sjögren’s syndrome, the usual dose is one tablet four times daily. Take a tablet with each of your three main meals, and also one at bedtime.

Does pilocarpine help with dry mouth?

Pilocarpine hydrochloride (Salagen) tablets are currently indicated for treatment of radiation-induced dry mouth. In 2 previous multicenter, double-blind, placebo-controlled trials,8,9 use of pilocarpine tablets provided significant relief to patients with radiation-induced dry mouth.

Does pilocarpine raise blood pressure?

Pilocarpine strongly increases arterial pressure which activates baroreceptors, thereby enhancing the activity of NTS and CVLM neurons, before the release of inhibitory signals in the RVLM trying to reduce sympathetic activation.

Does pilocarpine increase blood pressure?

Pilocarpine may have paradoxical effects on the cardiovascular system. The expected effect of a muscarinic agonist is vasodepression, but administration of Pilocarpine may produce hypertension after a brief episode of hypotension.

Can you use pilocarpine long term?

A recent multi-center study in SS patients suggests that oral pilocarpine is effective and safe for long-term administration.

How does pilocarpine raise blood pressure?

Does pilocarpine increase heart rate?

Acetylcholine and Pilocarpine slowed the heart rate when they were applied. Conversely, the addition of Epinephrine and Atropine + Acetylcholine increased the heart rate.

What are the contraindications of pilocarpine?

Who should not take PILOCARPINE HCL?

mental problems.
detachment of the retina of the eye.
inflammation of the iris – the colored part of the eyeball.
closed angle glaucoma.
high blood pressure.
low blood pressure.
asthma attack.
bronchospasm.

Can pilocarpine raise blood pressure?

Does pilocarpine decrease blood pressure?

Direct administration of pilocarpine to the fetus resulted in an immediate dose-dependent decrease in both systolic and diastolic blood pressure and a rapid fall in FHR.

What conditions does pilocarpine HCl treat?

Pilocarpine Hcl. This medication is used to treat symptoms of dry mouth due to a certain immune disease (Sjogren’s syndrome) or from saliva gland damage due to radiation treatments of the head/neck for cancer. Pilocarpine belongs to a class of drugs known as cholinergic agonists.

Who have High blood pressure with Pilocarpine hydrochloride – from FDA reports. High blood pressure is found among people who take Pilocarpine hydrochloride, especially for people who are female, 60+ old also take medication Folic Acid, and have Rheumatoid arthritis.

What is pilocarpine prescribed for?

Pilocarpine is prescribed to relieve dry mouth (sometimes called xerostomia) brought on by radiotherapy to the head or neck. Pilocarpine can also be used to relieve some of the symptoms of Sjögren’s syndrome.

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5mg Cialis Daily Use These consist of a past of eyesight reduction, low or high blood stress, stomach abscess, any kind of other eye troubles, renal or liver illness, a past of a stroke or a heart strike, irregular heartbeats or coronary infarction, several myeloma, leukemia, or sickle cell anemia.

What is pilocarpine hcl used for? Pilocarpine is used to treat dry mouth caused by radiotherapy in people with head and neck cancer and to treat dry mouth in people with Sjogren’s syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth).…