What kind of virus is a Picobirnavirus?
What kind of virus is a Picobirnavirus?
Picobirnavirus is a small ( pico, Spanish for small ), bisegmented ( bi, Latin for two ), double-stranded RNA virus. Picobirnaviruses were initially considered to be birna-like viruses, and the name was derived from birnavirus (bisegmented RNA), but the virions are much smaller (diameter 35 nm vs. 65 nm).
Where are the untranslated regions found in picornavirus?
An untranslated region (UTR) is found at both ends of the picornavirus genome. The 5′ UTR is usually longer, being around 500–1200 nucleotides (nt) in length, compared to that of the 3′ UTR, which is around 30–650 nt.
Is the genome of a picornavirus segmented or positive sense?
The genome is not segmented and positive-sense (the same sense as mammalian mRNA, being read 5′ to 3′). Unlike mammalian mRNA, picornaviruses do not have a 5′ cap, but a virally encoded protein known as VPg. However, like mammalian mRNA, the genome does have a poly (A) tail at the 3′ end.
What kind of RNA is needed for picornavirus replication?
Genomic RNAs of picornaviruses possess multiple RNA elements, and they are required for both negative- and positive-strand RNA synthesis. The cis-acting replication element (CRE) is required for replication.
Where is the VPg located in a picornavirus?
Unlike mammalian mRNA, picornaviruses do not have a 5′ cap, but a virally encoded protein known as VPg. However, like mammalian mRNA, the genome does have a poly (A) tail at the 3′ end. An untranslated region (UTR) is found at both ends of the picornavirus genome.
How many protomers are there in a picornavirus?
Picornaviruses are nonenveloped, with an icosahedral capsid. The capsid is an arrangement of 60 protomers in a tightly packed icosahedral structure. Each protomer consists of four polypeptides known as VP (viral protein) 1, 2, 3 and 4.
What kind of viruses are found in pisuviricota?
Clockwise from top left: TEM of avian coronavirus, penicilllium stoloniferum virus S, picobirnavirus, polio virus, calicivirus, astrovirus, plum pox virus, Nam Dinh virus. Center: phylogenetic tree of phylum Pisuviricota
What kind of virus is a Picobirnavirus? Picobirnavirus is a small ( pico, Spanish for small ), bisegmented ( bi, Latin for two ), double-stranded RNA virus. Picobirnaviruses were initially considered to be birna-like viruses, and the name was derived from birnavirus (bisegmented RNA), but the virions are much smaller (diameter 35 nm vs. 65…