Does neurofibromatosis affect pregnancy?
Does neurofibromatosis affect pregnancy?
There are different opinions about the implications of neurofibromatosis on pregnancy. Some authors have suggested an increased frequency of obstetric complications such as spontaneous miscarriage, preterm delivery, preeclampsia, intrauterine growth restriction, stillbirths and increased rate of caesarean section.
Can a baby have cafe au lait spots without neurofibromatosis?
The cafe-au-lait spots in themselves are harmless. It is not unusual for them to be passed off as mere “birthmarks”. Indeed, anyone can have 1 or 2 cafe-au-lait spots without having neurofibromatosis. The only significance to the cafe-au-lait spot is that it suggests the possibility that a person might have NF1.
What do cafe au lait spots signify?
They are caused by a collection of pigment-producing melanocytes in the epidermis of the skin. These spots are typically permanent and may grow or increase in number over time. Café au lait spots are often harmless but may be associated with syndromes such as neurofibromatosis type 1 and McCune–Albright syndrome.
Can neurofibromatosis be detected prenatally?
Neurofibromatosis screening tests can be performed prenatally (while a fetus is in utero) to help determine whether an individual will be born with the condition. However, prenatal neurofibromatosis tests are typically only given when one or both parents have the condition.
Should I have kids if I have NF1?
A: Yes, because anyone can have a child with NF1. If you have a mutation in the NF1 gene, there’s a 50 percent chance that another child will have the mutation.
Should I worry about café-au-lait spots?
Café au lait spots are usually harmless and don’t cause any uncomfortable symptoms or complications. But you shouldn’t ignore these spots, especially if you have more than a handful on your body. This could indicate an underlying genetic disorder.
What is Watson’s disease?
Watson syndrome is an autosomal dominant condition characterized by the presence of pulmonary valvular stenosis, cafe au lait spots, and mild mental retardation. These features are also sometimes observed in neurofibromatosis type 1 (NF1). It has been suggested that Watson syndrome is caused by mutations in NF1 gene.
How do you get rid of a café-au-lait birthmark?
Café-au-lait spots can be removed with lasers (highly concentrated light energy) but often return. Vascular birthmarks, on the other hand, can be treated. The exception is macular stains, which usually fade away on their own; ones at the back of the neck may be more persistent but are not very noticeable.
How do I know if my baby has neurofibromatosis?
Light brown spots on the skin called café-au-lait spots. These are the most common signs of NF, and they often appear at birth or in the first years of life. They’re harmless, but if your child has more than six, she probably has NF1. Freckles in the armpits or groin area also are signs of NF1.
Can I have a baby if I have NF1?
Can a child have only cafe au lait spots?
However, when the child has only cafe au lait spots, we need to carefully examine the characteristics of the spots to find out if they are the spots typically found in NF1 or if they are atypical spots, that is, they are not associated with NF1. First question: How to characterize the Café-au-lait spots(CALM)?
What does Cafe au lait mean for neurofibromatosis?
My 7-week-old grandson has 7 cafe-au-lait spots. What does this mean about his chances of developing neurofibromatosis? Both Joseph (John) Merrick, the Elephant Man, and Quasimodo, the Hunchback of Notre Dame, are dramatic examples that have shaped our perceptions of neurofibromatosis.
How many NF1 spots are there in Cafe au lait?
In summary, up to 3 typical spots, there is probably no associated disorder; 3 to 5 spots, we may think of other disorders; 6 or more stains, act as if it were NF1. Third question: Should we do the genetic test in a small child when it only presents only CALMS?
What kind of birthmark is Cafe au lait?
Café-au-lait spots are a classic feature of this disease. These flat birthmarks with distinct edges are a bit darker than the surrounding skin. In light-skinned individuals, they are the color of coffee with lots of cream.
Does neurofibromatosis affect pregnancy? There are different opinions about the implications of neurofibromatosis on pregnancy. Some authors have suggested an increased frequency of obstetric complications such as spontaneous miscarriage, preterm delivery, preeclampsia, intrauterine growth restriction, stillbirths and increased rate of caesarean section. Can a baby have cafe au lait spots without neurofibromatosis? The cafe-au-lait spots…