What are lymphocyte markers?

Lymphocyte surface markers are used to determine if there is an abnormal (clonal) population of lymphocytes present in the peripheral blood. The test relies on fixing antibodies to cell surface markers and looking for a particular monoclonal population.

What is a good percentage for lymphocytes?

20% to 40%
Normal Results Lymphocytes: 20% to 40% Monocytes: 2% to 8%

What is a lymphocyte test for?

They help your immune system by making antibodies and other substances that battle cancer and infections. They also kill cells that are infected or that are foreign to your body. This test looks at 3 types of lymphocytes to see how well your immune system is working: B lymphocytes (B cells).

Is 40% lymphocytes good?

Lymphocytes normally represent 20% to 40% of circulating white blood cells. When the percentage of lymphocytes exceeds 40%, it is recognized as relative lymphocytosis.

What happens if absolute lymphocyte count is high?

High lymphocyte blood levels indicate your body is dealing with an infection or other inflammatory condition. Most often, a temporarily high lymphocyte count is a normal effect of your body’s immune system working. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia.

Where are the markers on a lymphoma cell?

On the surface of lymphocytes, the cells that are transformed to lymphomas, lie some unique molecules. These were named ‘cluster differentiation’ or CD markers. As normal lymphocytes develop from new cells to mature cells, these markers change.

How are CD markers used to identify cells?

The CD system is commonly used as cell markers; this allows cells to be defined based on what molecules are present on their surface. These markers are often used to associate cells with certain immune functions or properties.

Are there reference ranges for peripheral blood lymphocytes?

The reference values of peripheral blood lymphocyte subsets were analyzed in healthy adolescent and adult population of South Florida. This study indicates the need for periodic evaluation and establishment of lymphocyte reference ranges for patient population served based on gender and age since th …

Is there a correlation between lymphocyte count and CD4 count?

Absolute lymphocyte counts showed a positive correlation with the absolute counts of CD3+, CD4+, CD8+, CD19+, CD16+CD56+, CD45RO+ and CD45RA+ cells (all correlations with P<0.0001 except CD45RO [P=0.01] and CD45RA [P=0.03]).

What are lymphocyte markers? Lymphocyte surface markers are used to determine if there is an abnormal (clonal) population of lymphocytes present in the peripheral blood. The test relies on fixing antibodies to cell surface markers and looking for a particular monoclonal population. What is a good percentage for lymphocytes? 20% to 40% Normal Results Lymphocytes:…