What is LKM 1 antibody IgG?

Liver Kidney Microsomal (LKM-1) Antibody (IgG) – The presence of LKM-1 antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH-2).

What is anti Lkm blood test?

This test detects and measures the amount (titer) of anti-LKM-1 (or antibody against CYP2D6) in the blood. Autoimmune hepatitis is an acute or chronic inflammation of the liver that can lead to liver cirrhosis and, in some cases, to liver failure.

What is actin smooth muscle antibody test for?

The smooth muscle (SMA) or actin antibody test is primarily ordered along with antinuclear antibodies (ANA) and liver kidney microsomal type 1 (LKM-1) antibodies to help diagnose autoimmune hepatitis and to differentiate between the two major types of autoimmune hepatitis, type 1 and type 2.

How does autoimmune hepatitis affect the body?

Autoimmune hepatitis occurs when your body’s infection-fighting system (immune system) attacks your liver cells. This causes swelling, inflammation and liver damage. It is a long-term or chronic inflammatory liver disease.

What is SLA patient?

Anti-Soluble-Liver-Antigen autoantibodies (SLA) are specifically associated with type 1 and type 2 autoimmune hepatitis and more closely related to patients who relapse after steroid therapy.

What is the normal range for smooth muscle antibody test?

Reference Range: F-Actin (Smooth Muscle) Ab, IgG by ELISA 19 Units or less Negative 20-30 Units Weak Positive – Suggest repeat testing in two to three weeks with fresh specimen. 31 Units or greater Positive – Suggestive of autoimmune hepatitis or chronic active hepatitis.

What does the anti LKM blood test look for?

Antibodies to liver and kidney microsomes, anti-LKM This test looks for a certain type of antibody in your child’s blood. The antibody is called liver kidney microsomal antibody. Hepatitis is a condition in which the liver is inflamed. Some types of hepatitis are caused by a hepatitis virus. Autoimmune hepatitis can be either type 1 or type 2.

What kind of hepatitis is associated with anti LKM-1 antibodies?

The development of anti-LKM-1 antibodies is strongly associated with type 2 autoimmune hepatitis. This test detects and measures the amount (titer) of anti-LKM-1 (or antibody against CYP2D6) in the blood. Autoimmune hepatitis is an acute or chronic inflammation of the liver that can lead to liver cirrhosis and, in some cases, to liver failure.

How are LKM antibodies used to diagnose AIH 2?

The detection of LKM-1 antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH-2). LKM antibodies are markers of AIH-2 which usually begins in childhood and generally affects children younger than 18 years of age. LKM antibodies are associated with a more serious progression of the disease.

How is anti LKM-1 related to other autoimmune disorders?

Levels of anti-LKM-1 are not closely related to the severity of a person’s symptoms or to that person’s prognosis. Levels may vary over time. Those with type 2 autoimmune hepatitis may also have other autoimmune disorders, such as diabetes or thyroiditis.

What is LKM 1 antibody IgG? Liver Kidney Microsomal (LKM-1) Antibody (IgG) – The presence of LKM-1 antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH-2). What is anti Lkm blood test? This test detects and measures…