What is Neo-Mercazole used for?
What is Neo-Mercazole used for?
NEO-MERCAZOLE® contains the active ingredient carbimazole. NEO-MERCAZOLE® is used to reduce the formation of thyroid hormones in people with an over- active thyroid gland. The condition is called hyperthyroidism. NEO- MERCAZOLE® may be used alone or together with other treatments for hyperthyroidism.
What is the mechanism of action of carbimazole?
Pharmacology and mechanism of action It is a prodrug converted to methimazole after administration. Ten mg of carbimazole is equivalent to 6 mg methimazole. Like methimazole, the action is to serve as substrate for thyroid peroxidase (TPO) and inhibits it and decreases incorporation of iodide into tyrosine molecules.
What is the mechanism of action for carbimazole Neo-Mercazole a medication used to treat hyperthyroidism?
Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).
How do I stop taking Neo-Mercazole?
No, you should not stop taking Neo-Mercazole 5 Tablet even if you start feeling better. You may have to take it for several months depending on your investigations. The duration of the treatment will continue till the thyroid hormone levels return to normal.
What are the side effects of neo Mercazole?
The most common minor side effects are nausea, headache, arthralgia and mild gastric distress. Mild skin rashes and pruritus can occur and these often respond to antihistamines without discontinuation of the medicine….The following are some symptoms which may or may not occur:
- skin rash.
- extreme tiredness.
Can carbimazole cause liver damage?
Carbimazole causes intracanalicular cholestasis whilst propylthiouracil causes hepatocellular injury. Therefore thyrostatic medication can be interchanged without increasing risk of further liver damage. Thionamide-induced liver damage is an idiosyncratic reaction, usually occurs within first three months of treatment.
What are side effects of Neomercazole?
Tell your doctor or pharmacist if you notice any of the following and they worry you:
- pain in joints.
- stomach upsets.
- skin rashes.
- loss of sense of taste.
- hair loss.
How long can you take neo Mercazole?
Once a remission has been secured, maintenance dosage should be continued for at least 12 months, and up to 2 years of treatment may be required. If thyroidectomy is intended, it can be carried out once the euthyroid state is achieved with Neo-Mercazole, which is then discontinued.
When can I stop taking NeoMercazole?
Carbimazole should be stopped temporarily at the time of administration of radio-iodine (to avoid thyroid crisis). Patients unable to comply with the instructions for use or who cannot be monitored regularly should not be treated with carbimazole.
What kind of Medicine is neo mercazole used for?
What Neo-Mercazole is used for. Neo-Mercazole contains the active ingredient carbimazole. This medicine is used to treat hyperthyroidism or overactive thyroid gland (a condition where the thyroid gland produces too much thyroid hormone).
How does neo mercazole work on the thyroid?
The medication transforms into methimazole after the absorption, which aids in the antithyroid functionality of drug. It decreases the uptake of inorganic iodine by the thyroid gland. What are the interactions of Neo-Mercazole 5Mg Tablet ?
When to take neo mercazole 5 with or without food?
It is used in the treatment of hyperthyroidism. It reduces the amount of thyroid hormones produced by the thyroid gland. Neo-Mercazole 5 Tablet may be used alone or in combination with other medicines. It can be taken with or without food. It should be taken exactly as prescribed by your doctor.
What are the side effects of neo mercazole 10mg?
What are the side effects of Neo-Mercazole 10Mg Tablet ? 1 Skin Rash 2 Hair Loss 3 Hair Discolouration 4 Joint Pain 5 Change In Taste 6 Fever 7 Liver Damage 8 Low Wbc Count
What is Neo-Mercazole used for? NEO-MERCAZOLE® contains the active ingredient carbimazole. NEO-MERCAZOLE® is used to reduce the formation of thyroid hormones in people with an over- active thyroid gland. The condition is called hyperthyroidism. NEO- MERCAZOLE® may be used alone or together with other treatments for hyperthyroidism. What is the mechanism of action of carbimazole?…