What is refractory lymphoma?

The term “refractory” is used to describe when the lymphoma does not respond to treatment (meaning that the cancer cells continue to grow) or when the response to treatment does not last very long.

How is RR DLBCL treated?

Salvage high-dose chemotherapy followed by autologous stem cell transplantation is the standard of care for chemosensitive relapses in DLBCL. Various salvage regimens are available, but the quest for an optimal regimen continues. The addition of rituximab to the salvage regimen has improved the outcome of RR DLBCL.

What is refractory non Hodgkin’s lymphoma?

Some patients still have lymphoma cells in their bone marrow after NHL treatment. This is called refractory non-Hodgkin lymphoma. Some patients have a return of lymphoma cells in the marrow and a decrease in normal blood cells after remission.

Can you survive B cell lymphoma?

Below are the 5-year relative survival rates for two common types of NHL – diffuse large B-cell lymphoma and follicular lymphoma – based on people diagnosed between 2010 and 2016….5-year relative survival rates for NHL.

SEER Stage	5-Year Relative Survival Rate
Distant	85%
All SEER stages combined	89%

When to use rituximab and ice for lymphoma?

Rituximab and ICE as second-line therapy before autologous stem cell transplantation for relapsed or primary refractory diffuse large B-cell lymphoma Blood. 2004 May 15;103(10):3684-8.doi: 10.1182/blood-2003-11-3911. Epub 2004 Jan 22. Authors

What are the effects of rice on DLBCL?

RICE appears to induce very high CR rates in patients with relapsed and refractory DLBCL; however, further studies are necessary to determine whether this treatment regimen will improve outcomes after ASCT. Publication types Clinical Trial Research Support, Non-U.S. Gov’t

When to use rituximab or carboplatin for aggressive lymphoma?

The purpose of this retrospective analysis was to evaluate the results of the R-ICE (rituximab, ifosfamide, carboplatin, etoposide) protocol alone as compared to R-ICE followed by high-dos … For patients aged 60 years or older, the treatment of relapsed aggressive B-cell lymphomas remains challenging.

What are the chances of survival after Rice?

Progression-free survival rates of patients who underwent transplantation after RICE were marginally better than those of 95 consecutive historical control patients who underwent transplantation after ICE (54% vs 43% at 2 years; P =.25).

What is refractory lymphoma? The term “refractory” is used to describe when the lymphoma does not respond to treatment (meaning that the cancer cells continue to grow) or when the response to treatment does not last very long. How is RR DLBCL treated? Salvage high-dose chemotherapy followed by autologous stem cell transplantation is the standard…