## What is the balanced equation for the synthesis of aspirin?

The balanced equation is: C4H6O3+C7H6O3→C9H8O4+C2H4O2.In a laboratory synthesis, a student begins with 5.00 mL of acetic anhydride (density = 1.08 g / mL) and 2.08 g of salicylic acid. Once the reaction is complete, the student collects 2.47g of aspirin.

How is acetylsalicylic acid synthesized?

Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.

What is the reaction involved during synthesis of aspirin from salicylic acid?

To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. Since acetic acid is very soluble in water, it is easily separated from the aspirin product. The aspirin isolated in this step is the “crude product”.

### How do you calculate aspirin yield?

Using the theoretical and actual you can calculate percent yield.

1. Actual Yield of Aspirin in lab after filtered/dried (mock value) = 370 g.
2. Mass of Theoretical Yield of Aspirin (mock value) = 360.3 g.
3. Percent Yield = (Actual ÷ Theoretical) x 100 = (370 ÷ 360.3) x 100 = 103 %

What is acetylation reaction explain with example?

When the hydrogen of an alcohol is replaced with an acetyl group via an acetylation reaction, the final product formed is an ester. One of the most common examples of an acetylation reaction is the acetylation of salicylic acid with acetic anhydride to afford acetic acid and acetylsalicylic acid as the products.

What is the reaction mechanism of aspirin?

The synthesis of aspirin is classified as an esterification reaction. Salicylic acid is treated with acetic anhydride, an acid derivative, causing a chemical reaction that turns salicylic acid’s hydroxyl group into an ester group (R-OH → R-OCOCH3).

#### What is the formula use in the calculation of percentage yield in the synthesis of aspirin?

Example: Start with 0.027moles of aspirin (limiting reagent) going to 0.027moles of salicylic acid. 3. Divide the number of grams of product obtained experimentally, by the number of grams obtained in the theoretical yield calculations and multiply by 100 to calculate the percent yield.

What is the chemical equation of acetylation?

What is meant by the term acetylation? The term ‘acetylation’ is used to denote the organic chemical reactions in which a hydrogen atom belonging to a compound is substituted with an acetyl group (which is a functional group with the general formula CH3C=O).

Is acylation and acetylation same?

The difference between acylation and acetylation is that introducing an acyl group to an organic compound is known as acylation. Whereas introducing an acetyl group to an organic compound is known as acetylation.

## How to synthesise acetyl salicylic acid ( aspirin )?

3623 mol The chemical name for Aspirin is Acetylsalicylic Acid. A balanced equation for the synthesis of Aspirin from Salicylic Acid and Acetic Anhydride is the following: Salicylic acid + acetic anhydride –> Acetylsalicylic acid + Acetic acid (C7H6O3) + (C4H6O3) –> (C9H8O4) + (C2H4O2) 0.

How to calculate the mass of acetyl salicylic acid?

Therefore moles acetylsalicylic acid (aspirin) = 0. 3623 mol To calculate the mass of aspirin that should be produced theoretically use the equation: m = mr * mol Mr of acetylsalicylic acid = 180 Therefore 180 * 0. 3623 = 65. 22g The above calculations show that theoretically there should be 65. 22g of aspirin produced.

How is acetylsalicylic acid used as a catalyst?

Salicylic acid acting as an alcohol is reacted with acetic anhydride acting as the acid in an esterification reaction to produce an ester, acetylsalicylic acid (aspirin). Concentrated sulfuric acid is used as a catalyst. Limiting Reagent and % Yield:

### How to calculate the molecular mass of aspirin?

The relative molecular mass of salicylic acid is 138. Therefore we are able to calculate the number of moles of salicylic acid using the equation: m = n/ Mr Moles of acetic anhydride 50/138 = 0. 3623 mol The chemical name for Aspirin is Acetylsalicylic Acid.

What is the balanced equation for the synthesis of aspirin? The balanced equation is: C4H6O3+C7H6O3→C9H8O4+C2H4O2.In a laboratory synthesis, a student begins with 5.00 mL of acetic anhydride (density = 1.08 g / mL) and 2.08 g of salicylic acid. Once the reaction is complete, the student collects 2.47g of aspirin. How is acetylsalicylic acid synthesized?…