What is the difference between myotonic dystrophy type 1 and type 2?

Myotonic dystrophy type 1 is caused by mutations in the DMPK gene, while type 2 results from mutations in the CNBP gene. The protein produced from the DMPK gene likely plays a role in communication within cells.

How many types of myotonic dystrophy are there?

There are two main types DM. DM type 1 (DM1) can be further classified as mild DM1, classic DM1 and congenital DM1. Mild DM1 is characterized by clouding of the lenses of the eyes (cataracts) and sustained muscle contractions (myotonia), in which the muscles do not relax after use.

What kind of muscle weakness does myotonic dystrophy cause?

This disease is characterized by progressive muscle loss and weakness. Myotonic dystrophy may be further classified into two types, and the two types may affect different muscles. People with myotonic dystrophy usually have prolonged muscle tensing (myotonia) and are not able to relax certain muscles after use.

What are the treatment options for myotonic dystrophy?

Treatment is aimed at managing symptoms of the disease. [7] Routine physical activity appears to help maintain muscle strength and endurance and to control musculoskeletal pain. [3] Canes, braces, walkers, and scooters can help as muscle weakness progresses.

How is congenital myotonic dystrophy type 1 diagnosed?

Congenital myotonic dystrophy type 1 occurs only when the disease is inherited from the mother. Myotonic dystrophy is diagnosed by doing a physical exam. A physical exam can identify the typical pattern of muscle wasting and weakness of the jaw and neck muscles and the presence of myotonia. Men may have frontal balding. [3] [4]

Can a person with myotonic dystrophy live a normal life?

People with myotonic dystrophy type 2 may have a normal lifespan. While mobility may be impaired at an early age, the ability to walk is often retained until around 60-years-old. Last updated: 8/22/2017

What is the difference between myotonic dystrophy type 1 and type 2? Myotonic dystrophy type 1 is caused by mutations in the DMPK gene, while type 2 results from mutations in the CNBP gene. The protein produced from the DMPK gene likely plays a role in communication within cells. How many types of myotonic dystrophy…