What is the difference between sitagliptin and alogliptin?

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don’t want to use an injectable medicine. Lowers your blood sugar. Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn’t work as well as insulin.

Which is better linagliptin or sitagliptin?

Conclusions: Based on the results, there was no significant difference between the two drugs, i.e. linagliptin and sitagliptin, in terms of efficacy; in other words, the efficacy of the two drugs was the same. Therefore, the use of these two drugs depends on their availability and cost.

How many types of gliptins are there?

There are at least seven different classes of agents used as monotherapy, or in combinations for the treatment of diabetes mellitus. These include metformin, sulphonylureas, meglinitides, alpha-glucosidase inhibitors, thiazolidinediones (TZD), glucagon like peptide-1 (GLP-1) agonists and insulin[1,2].

What is the side effect of Galvus Met?

Nausea, diarrhea, vomiting, stomach upset, sore throat, headache, dizziness are some of the common side effects that a person can suffer from while consuming Galvus Met. If you are consuming other diabetic medications like insulin, sulphonylurea, then you might suffer from low blood sugar.

Which Gliptin is best for type 2 diabetes?

Gliptins improve glycaemic control in type 2 diabetes Sitagliptin (Januvia), vildagliptin (Galvus) and saxagliptin (Onglyza) are dipeptidyl peptidase-4 (DPP-4) inhibitors.

When is the best time to take sitagliptin?

You can generally take the tablet at a time of day to suit you, but it is best to take your doses at the same time of day each day. You can take sitagliptin before or after a meal.

What drugs are gliptins?

Dipeptidyl peptidase-4 inhibitors (DPP-4s), also commonly called gliptins, are a relatively new class of drugs for the treatment of type 2 diabetes.

How are gliptins used in the beta cell system?

Gliptins represent a novel class of agents that improve beta cell health and suppress glucagon, resulting in improved post-prandial and fasting hyperglycemia. They function by augmenting the incretin system (GLP-1 and GIP) preventing their metabolism by dipeptidyl peptidase-4 (DPP-4).

Which is the best gliptin for your health?

This review focuses on gliptins (sitagliptin, vildagliptin, saxagliptin, linagliptin, and alogliptin) discussing pharmacokinetics, pharmacodynamics, efficacy, and safety. Content may be subject to copyright. therapies world over since years.

How are gliptins used to treat glycated haemoglobin?

Gliptins are a new class of oral anti-diabetic medication that prolong the physiological actions of GLP-1. Short term clinical trials show that gliptins cause a modest reduction in glycated haemoglobin when used as monotherapy or combination therapy, of around 0.7–1%.

How are gliptins an oral anti-diabetic agent?

Gliptins are a novel class of oral anti-diabetic agent that enhance and prolong the physiological actions of incretin hormones by competitively antagonizing the enzyme DPP-IV ( Figure 4 ).

What is the difference between sitagliptin and alogliptin? Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don’t want to use an injectable medicine. Lowers your blood sugar. Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn’t…