Which are the signs symptoms of transurethral resection TUR syndrome?

Transurethral resection of the prostrate (TURP) syndrome can cause a wide variety of symptoms that include asymptomatic hyponatremia, ECG changes, fatigue, vomiting, confusion, visual loss, coma and death. General anaesthesia may mask some of the TURP syndrome’s symptoms.

What is the cause of TURP syndrome?

Transurethral resection of prostate (TURP) syndrome is a systemic complication of transurethral resection of the prostate or bladder tumours, caused by excessive absorption of electrolyte-free irrigation fluids.

How do you treat TURP syndrome?

Management of severe TURP syndrome. Diuretic therapy (e.g. i.v. furosemide 40 mg) is only recommended to treat acute pulmonary oedema caused by the transient hypervolaemia. Furosemide worsens hyponatraemia, but is effective at removing free water.

Is pulmonary edema a symptom of TURP syndrome?

Case Presentation. We report a patient who suffered severe TURP syndrome after transurethral resection of the prostate procedure. Clinical manifestations were pulmonary edema and respiratory failure. The concentration of Na+ was 112.6 mmol/l, which was severe hyponatremia.

What fluid is used in TURP?

Glycine solution is the most commonly used irrigant in TURP. Many studies performed on human denoting that glycine absorption causes echocardiogram changes and it is associated with increased troponin I [6].

How do you prevent TURP syndrome?

THE IDEAL IRRIGATION FLUID

transparent (for good visibility)
electrically non-conductive (to prevent dispersion of the diathermy current)
isotonic.
non-toxic.
non-haemolytic when absorbed.
easy to sterilize.
inexpensive.

What is the most common complication of TURP?

Retrograde ejaculation is the most common long-term complication of TURP and can occur in as many as 90% of cases.

Why is glycine used for TURP?

Glycine 1.5% is used because it is less costly, only slightly hypoosmolar and nonelectrolyte. Glycine is an inhibitory neurotransmitter and if large amounts are absorbed the patient can develop central nervous system toxicity, which includes transient blindness and encephalopathy.

What is post TURP syndrome?

Abstract. Absorption of large volumes of irrigation fluid during transurethral resection of the prostate (TURP) can produce hyponatremia, coma, blindness, and cardiorespiratory depression. This has been termed the “post-TURP syndrome.” The pathophysiology and management of this syndrome are controversial.

What are the side effects of TURP syndrome?

TURP syndrome is due to absorption of irrigation fluid via open prostatic venous sinuses in sufficient quantities to cause hypervolaemia, hyponatraemia and hyperglycinaemia (if glycine is being used) leading to encephalopathy and cardiac, respiratory and renal failure.

How to diagnose TURP syndrome under general anaesthesia?

Under general anaesthesia, the neurological manifestations are masked and so the diagnosis of TURP Syndrome is difficult and often delayed. The cardiovascular signs predominate. An unexplained rise in BP followed by a fall often associated with refractory bradycardia.

How much glycine do you need for TURP syndrome?

Patients usually absorb around 20mL/min, average absorption during a case is ~ 1.5L and depends on: symptoms primarily arise from the effects of glycine, which acts as an inhibitory CNS neurotransmitter at GABA receptors and paradoxically potentiates NMDA receptors

Which is the best TURP solution for neurosurgery?

Sorbitol 2.7% and mannitol 0.54% is another solution commonly used and is also nonelectrolyte, iso-osmolar, rapidly cleared from plasma, but is more costly and can result in fluid overload. Morgan and Mikhail’s Clinical Anesthesiology. p 760.

Which are the signs symptoms of transurethral resection TUR syndrome? Transurethral resection of the prostrate (TURP) syndrome can cause a wide variety of symptoms that include asymptomatic hyponatremia, ECG changes, fatigue, vomiting, confusion, visual loss, coma and death. General anaesthesia may mask some of the TURP syndrome’s symptoms. What is the cause of TURP syndrome?…